Catálogo de la Colección "Derecho, Economía y Sociedad" Sitio Oficial de la Facultad de Derecho de la Universidad de Buenos Aires

Regulación jurídica de las biotecnologías

Curso dictado por la Dra. Teodora Zamudio

Equipo de docencia e investigación UBA~Derecho

Actualidad | Normativa | Jurisprudencia | Doctrina |Enlaces |Mapa de carpetas

 Glosario

Investigación e implementación de sistemas de identificación de individuos por tecnicas de biologia molecular (Cap 7 y 8)


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... con especial referencia a los estudios post-mortem.

Tesista  Gustavo Adolfo Penacino.

Director: Dr. Daniel Corach.

Tesis doctoral  aprobada con Sobresaliente 11 de diciembre de 1997 Area Biologia Molecular

Universidad de Buenos Aires, Argentina.

Contacto actual con el autor: Director Unidad de Análisis de ADN, Colegio Oficial de Farmacéuticos y Bioquímicos, Rocamora 4045, Buenos Aires, Argentina. Tel/fax: (54) (11) 4862-1142. E-mail: gpenacino@wwiecorp.com. Website: www.adn.ac www.secretpaternity.com

7 Conclusiones

8 Bibliografia

 

1 Resumen 2 Introducción 3 Materiales 4 Métodos 5 Resultados 6 Discusión 7 Conclusiones 8 Bibliografia

7 Conclusiones

• En el presente trabajo se desarrollaron, implementaron y validaron las técnicas de extracción de ADN a partir de manchas de fluídos y de tejidos celulares obtenidos de cadáveres en diferente estado de conservación.

• El estudio de los diferentes métodos de purificación del ADN extraído, permitió optimizar la eficiencia de los estudios posteriores.

• Se compararon los distintos sistemas variables conocidos para diferentes materiales de interés forense, permitiendo una selección de los más adecuados para cada caso.

• Se desarrollaron nuevos sistemas combinados de caracterización molecular para análisis de ADN altamente degradado, obtenido a partir de manchas de fluídos biológicos y/o restos humanos.

• Del estudio de pelos en diferentes condiciones, pudo establecerse que sólo los que poseen bulbo resultan adecuados para al análisis de ADN microsatélite.

• Se determinó la utilidad de las uñas en la identificación de cadáveres.

• Se correlacionaron las características tanatológicas del material de análisis y la investigación molecular basada en estudios de ADN.

• Se determinó que la pulpa dental es el material de elección para el análisis de ADN proveniente de cadáveres quemados.

• Se establecieron estrategias de análisis de restos humanos procedentes de desastres en masa.

• Se efectuaron estudios preliminares de marcadores hipervariables ubicados en el cromosoma Y humano, concluyéndose que son aptos para el análisis forense.

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